Publication:
Optimising Investments in the Tuberculosis Response of Gauteng Province, South Africa: Findings from a Pilot Application of the Optima TB Model

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dc.contributor.authorWorld Bank
dc.contributor.authorOptima Consortium for Decision Sciences
dc.contributor.authorGovernment of South Africa
dc.date.accessioned2020-02-25T20:01:26Z
dc.date.available2020-02-25T20:01:26Z
dc.date.issued2019-03
dc.description.abstractSouth Africa remains a high-burden country for tuberculosis (TB) and multi-drug resistant TB (MDR-TB) with an underlying generalised HIV epidemic. TB funding must therefore be allocated to interventions which provide high impact to prevent TB transmission, identify TB cases and treat them successfully. This report presents the findings from a pilot application of the Optima TB model in Gauteng Province, where many challenges remain to sustainably reduce TB. The modelling analysis focused on relevant intervention scenarios and optimal resource allocation to achieve the 2022 TB targets, using the mathematical optimisation feature of the tool. Findings suggest that further reductions in TB prevalence and deaths are possible through improved allocative efficiency. Several scenarios highlight opportunities especially in HIV negative populations by improving the TB care cascade with higher diagnosis rates, enhanced linkage to treatment and better MDR treatment outcomes using shorter drug regimens. The same budget allocated differently could, by 2022, reduce active TB infections by up to 40 and reduce TB deaths by up to 30 perent among HIV positive and HIV negative populations. The study provided valuable input into the refinement of the Optima TB model, especially for the HIV/TB co-epidemic setting. The model outputs support Gauteng's focus on improving the care cascade and innovating MDR-TB treatment.en
dc.identifierhttp://documents.worldbank.org/curated/en/772111581370318152/Optimising-Investments-in-the-Tuberculosis-Response-of-Gauteng-Province-South-Africa-Findings-from-a-Pilot-Application-of-the-Optima-TB-Model
dc.identifier.doi10.1596/33377
dc.identifier.urihttps://hdl.handle.net/10986/33377
dc.languageEnglish
dc.publisherWorld Bank, Washington, DC
dc.rightsCC BY 3.0 IGO
dc.rights.holderWorld Bank
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/igo
dc.subjectTUBERCULOSIS
dc.subjectOPTIMA MODEL
dc.subjectHEALTH CARE
dc.subjectDISEASE CONTROL
dc.subjectALLOCATIVE EFFICIENCY
dc.subjectHEALTH EXPENDITURE
dc.titleOptimising Investments in the Tuberculosis Response of Gauteng Province, South Africaen
dc.title.subtitleFindings from a Pilot Application of the Optima TB Modelen
dc.typeReporten
dc.typeRapportfr
dc.typeInformees
dspace.entity.typePublication
okr.crossref.titleOptimising Investments in the Tuberculosis Response of Gauteng Province, South Africa
okr.date.disclosure2020-02-10
okr.doctypeEconomic & Sector Work
okr.doctypeEconomic & Sector Work::Other Health Study
okr.docurlhttp://documents.worldbank.org/curated/en/772111581370318152/Optimising-Investments-in-the-Tuberculosis-Response-of-Gauteng-Province-South-Africa-Findings-from-a-Pilot-Application-of-the-Optima-TB-Model
okr.guid772111581370318152
okr.identifier.doi10.1596/33377
okr.identifier.doihttps://doi.org/10.1596/33377
okr.identifier.externaldocumentum090224b0875d0422_2_0
okr.identifier.internaldocumentum31772136
okr.identifier.report145899
okr.importedtrueen
okr.language.supporteden
okr.pdfurlhttp://documents.worldbank.org/curated/en/772111581370318152/pdf/Optimising-Investments-in-the-Tuberculosis-Response-of-Gauteng-Province-South-Africa-Findings-from-a-Pilot-Application-of-the-Optima-TB-Model.pdfen
okr.region.administrativeAfrica
okr.region.countrySouth Africa
okr.topicHealth, Nutrition and Population::Health Economics & Finance
okr.topicHealth, Nutrition and Population::Public Health Promotion
okr.topicHealth, Nutrition and Population::Tuberculosis
okr.topicPublic Sector Development::Public Sector Expenditure Policy
okr.unitHNP Global (HHNGE)
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